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中国医药导刊 ›› 2024, Vol. 26 ›› Issue (1): 66-72.

• 精准医疗良好实践案例:创新实践 • 上一篇    下一篇

爱沙尼亚个性化医疗领域项目进展与经验

梁安琪12, 韩洞明12, 李建康1, 高雅1, 金鑫1*   

  1. 1.深圳华大生命科学研究院,广东 深圳 518083;
    2.中国科学院大学生命科学学院,北京 100049
  • 收稿日期:2024-01-04 出版日期:2024-01-28 发布日期:2024-01-28
  • 基金资助:
    国家重点研发计划资助项目,科技部重点研发计划“政府间国际科技创新合作”重点专项[项目编号:2021YFE0192400;项目名称:中国-欧盟国际精准医疗领域合作支持计划(IC2PerMed)]

Estonian Project Progress and Experience in Personalized Medicine

  1. 1.BGI Research Guangdong Shenzhen 518083, China
    2.College of Life Sciences University of Chinese Academy of Sciences Beijing 100049, China
  • Received:2024-01-04 Online:2024-01-28 Published:2024-01-28

摘要:

个性化医疗的发展在国际社会中备受瞩目,已逐步成为新的研究热点之一。个性化医疗旨在利用健康行为、医学检测结果、症状、家族史、环境因素和基因组信息等个人医疗信息,实施一种新的医疗实践来诊断和治疗疾病,通过采用更个性化的方法、有针对性的筛查方案、早期干预和治疗来改善患者的健康状况,将医疗实践从反应性治疗转变为预防性保健。这种个性化的方法有助于提前发现和处理健康问题,而不是等到疾病出现后再进行治疗。爱沙尼亚作为国际精准医疗联盟(ICPerMed)成员国之一,在个性化医疗领域有着丰富的经验。自21世纪以来,爱沙尼亚政府大力发展医疗保健领域,为个性化医疗的发展奠定了基础。爱沙尼亚政府牵头在全国范围内发起了建立以人群为基础的生物样本库的行动,该生物样本库中包含各类疾病与其生物标志物,以及与患者生活方式的对应关系,为研究常见疾病和性状提供便利。本研究主要介绍爱沙尼亚最近十年在个性化医疗领域完成的项目及其经验,为我国精准医疗创新发展提供借鉴参考。


关键词: 爱沙尼亚, 个性化医疗, 临床决策支持系统, 国际精准医疗联盟

Abstract:

The development of personalized medicine has attracted much attention in the international community and it has gradually become one of the new research hotspots. Personalized medicine aims to implement a new medical practice to diagnose and treat diseases using personal medical information including health behaviors medical test results symptoms family history environmental factors and genomic information. It transform medical practice from reactive treatment to preventive care by adopting a more personalized approach targeted screening protocols early intervention and treatment to improve patient health. This personalized approach helps to detect and deal with health problems in advance rather than waiting until the disease appears before treatment. As a member of the International Consortium for Personalized Medicine ICPerMed), Estonia has extensive experience in the field of personalized medicine. Since the 21st century the Estonian government has vigorously developed the field of healthcare laying the foundation for the development of personalized medicine. In Europe Estonia has spearheaded the nationwide initiative to establish a population-based Estonian biobank that includes the mapping of diseases to their biomarkers and patients' lifestyles facilitating the study of common diseases and traits. This article mainly introduces Estonia's projects completed in the field of personalized medicine in the past ten years and summarizes its experience so as to provide reference for the development of precision medicine in China.

Key words: Estonia; Personalized medicine; Clinical decision support systems; , International Consortium for Personalized Medicine

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