关键词: 参附注射液, 艾灸, 脓毒性休克

Abstract:

Objective： To exploring the clinical efficacy of Shenfu injection combined with moxibustion in the treatment of septic shock caused by Yang Qi burst.Methods： 74 patients with yang gas burst type septic shock in our hospital were randomly divided into two groups， with 37 cases in each group. The control group received conventional Western medicine treatment， while the observation group received additional treatment with Shenfu injection and moxibustion therapy on the basis of the control group. Both groups of patients were evaluated for efficacy after 7 days of treatment. Compare the levels of inflammatory factors such as tumor necrosis factor alpha （TNF-α）， interleukin-6 （IL-6）， and PCT in the serum of two groups of patients before and after treatment， as well as the Sequential Organ Failure （SOFA） score and Acute Physiology and Chronic Health Status （APACHE II） score. Compare the total dose of vasoactive drugs used， ICU stay， and treatment efficacy between the two groups.Results： After treatment， the serum levels of TNF-α， IL-6， PCT， SOFA score， and APACHE II score in the observation group were significantly lower than those in the control group （P<0.05）. The total dose of vasoactive drugs and ICU stay in the observation group were significantly lower than those in the control group （P<0.05）. The total effective rate of the observation group was 86.5%， while that of the control group was 62.2% （P<0.05）.Conclusion： The combination of Shenfu injection and moxibustion can effectively reduce the levels of inflammatory factors， improve organ function， reduce the dosage of vasoactive drugs and ICU stay， and increase therapeutic efficacy in the treatment of Yang Qi burst type septic shock.

Key words:  ,  , Shenfu Injection； , Moxibustion； , Septic shock