关键词: font-size:medium, ">小儿肺咳颗粒；阿奇霉素；喘息性支气管炎；肺功能；炎性因子

Abstract: Objective： To observe the effects of xiao′er feike granules combined with azithromycin on lung function and inflammatory cytokines in children with asthmatic bronchitis. Methods： 90 cases of children with asthmatic bronchitis were randomly divided into the control group and the observation group， and 45 cases in each group. Azithromycin， xiao′er feike granules combined with azithromycin were given respectively in the two groups for 5 d. The clinical symptoms， lung function and inflammatory cytokines were observed before and after treatment， and the clinical efficacy and adverse reactions were compared between the two groups. Results： The total effective rate was 97.7% (43/44) in the observation group， which was higher than 80.5% (33/41) in the control group (P<0.05). The disappearance time of clinical symptoms in the observation group was shorter than that in the control group (P<0.05). Compared with the control group after treatment， the lung function in the observation group was improved (P<0.05)， and the inflammatory cytokines were reduced (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion： Xiao′er feike granules combined with azithromycin can effectively improve lung function and inflammatory cytokines in children with asthmatic bronchitis.
   

Key words: font-size:medium, ">Xiao′er feike granules； Azithromycin； Asthmatic bronchitis； Lung function； Inflammatory cytokines