关键词: font-size:medium, ">呼吸与危重症科；抗菌药物；合理用药

Abstract: Objective：To investigate the use of antibiotics in pulmonary and critical care medicine (PCCM)department in our hospital， analyze the irrational use of antibiotics in PCCM department， and improve the rational use of antibiotics. Methods： A total of 669 discharged patients from the PCCM department in our hospital in 2020 were randomly selected.82 patients who died， transferred out within 5 d after admission， or did not use antibiotics were excluded， and 587 patients were eventually included.Clinical data were obtained to conduct retrospective investigation and analysis on the use of antibiotics in patients. Results: A total of 1 339 patients were discharged from PCCM department in our hospital in 2020， among which 1 247 patients were treated with antibiotics， and the utilization rate of antibiotics was 93.13%. A total of 15 kinds of antibiotics were used in the 587 patients， and the top three antibiotics in the number of cases were piperacillin sodium and tazobactam sodium for injection， azithromycin for injection，levofloxacin hydrochloride for injection， respectively. Among the 587 patients，437 patients received antibiotic monotherapy and 150 patients received antibiotic combination therapy. 549 cases (93.52%)were treated with antibiotics for 3-14 d. Conclusion： The use of antibiotics in inpatients in PCCM department of our hospital are basic reasonable， but there arestill some irrational drug uses，such as inappropriatedrug selection，inappropriate dosing frequency.It is suggested that the management of the use of antibiotics should be strengthened， and clinical physicians and nursing staffs should strengthen the antibacterial drug related knowledge learning， thus effectively improve the level of the use of antibiotics.

Key words: Pulmonary and critical care medicine, Antibiotics, Rational drug use