Abstract: Since December 2019， a number of patients with Corona Virus Disease 2019（COVID-19） have been discovered in Wuhan， Hubei Province of China. With the rapid spread of the epidemic， COVID-19 was soon included as an acute respiratory infectious disease in the Class B infectious disease stipulated in the Law of the People′s Republic of China on the Prevention and Control of Infectious Diseases.It is managed according to Class A infectious diseases， and it has become a public problem in the society at present. Our hospital is the only designated hospital in Deyang City to treat this disease， and the department of infectious diseases is a designated treatment department. We actively responded to the epidemic， decisively isolated the source of infection， cut off transmission channels， strengthen management， and effectively prevented and controlled. At the same time， we also undertake the diagnosis and treatment of tuberculosis， AIDS， viral hepatitis and other types of infectious diseases. Therefore， it is particularly important to ensure the health of patients through strengthening the scientific management of the ward in infectious disease department， while effectively preventing and controlling and improving the treatment success rate of COVID-19 patients. In order to provide reference for ward management during the period of anti-epidemic in other hospitals， this article described about the ward management in COVID-19 epidemic situation.